GLENDALE, Ariz. (AP) — Patrick Mahomes threw for 360 yards and five touchdowns, lifting the Kansas City Chiefs to an impressive 44-21 road win over the Arizona Cardinals in the opener for both teams. The quarterback was playing his first NFL game against Kliff Kingsbury, who coached Mahomes in college at Texas Tech and now leads the Cardinals. Tight end Travis Kelce caught eight passes for 121 yards and a touchdown. It was his 30th career game with at least 100 yards receiving. Clyde Edwards-Helaire hauled in two touchdown passes.
GLENDALE, Ariz. (AP) — Kansas City Chiefs safety Justin Reid has added kicking duties to his resume. Reid was called into action after kicker Harrison Butker rolled his left ankle on a kickoff in the first quarter Sunday against the Arizona Cardinals. Butker was taken off the field on a cart, but later returned to the sideline. Reid made his first extra point attempt, but missed his second after the Chiefs took a 20-6 lead in the second quarter. He also boomed two kickoffs for touchbacks.
ARLINGTON, Texas (AP) — Tom Brady and Mike Evans connected on a punctuating touchdown, Leonard Fournette ran for 127 yards and the Tampa Bay Buccaneers dominated the Dallas Cowboys 19-3. Cowboys quarterback Dak Prescott suffered an injury to his throwing hand that owner Jerry Jones said will require surgery and force him to miss several weeks. Brady was in control throughout the first start for a 45-year-old quarterback in NFL history. He had a big assist from the defense in Todd Bowles’ debut as Tampa Bay’s coach following three seasons as defensive coordinator.
KANSAS CITY, Mo. (AP) — Brady Singer threw seven scoreless innings as the Kansas City Royals beat the Detroit Tigers 4-0 to salvage the finale of the three-game series. Detroit was shut out for the 20th time this season, the most in the majors. Singer allowed four hits and one walk with six strikeouts. Kansas City has won six of Singer’s last seven starts. Michael Massey hit his second home run of the season and Drew Waters added a two-run double to lead the Royals' offense. Bobby Witt Jr. had two hits and a double, his 51st extra-base hit to lead all major league rookies. Detroit starter Tyler Alexander allowed four runs on six hits over five innings.
PITTSBURGH (AP) — Albert Pujols hit his 697th home run, moving past Alex Rodriguez into fourth place on the career list and doing it in dramatic fashion with a ninth-inning drive that rallied the St. Louis Cardinals over the Pittsburgh Pirates 4-3. The NL Central-leading Cardinals trailed 2-1 when Pujols connected for a two-run drive. Pujols had tied Rodriguez with a home run Saturday night. Pujols trails Barry Bonds (762), Hank Aaron (755) and Babe Ruth (714) on the all-time homer chart. The 42-year-old Pujols has 21 games left in his 22nd and final season in the big leagues. He’s hit 18 home runs this season.
UNDATED (AP) — Georgia has reclaimed the top spot in The Associated Press college football poll and Oklahoma State, Kentucky and Arkansas moved into the top 10 after an upset-filled weekend. The defending national champion Bulldogs started the season at No. 3 in the AP Top 25. It took them two weeks to get back to where they spent most of last year. Georgia received 53 of 63 first-place votes. No. 2 Alabama, which needed a late field goal to hold off Texas, received nine first-place votes and No. 3 Ohio State got one. No. 4 Michigan and No. 5 Clemson held their places. Oklahoma moved up a spot to No. 6. And Southern California jumped three places to No. 7. Notre Dame tumbled out all the way from No. 8 to snap a streak of 80 straight poll appearances.
LINCOLN, Neb. (AP) — Nebraska has fired football coach Scott Frost after a 1-2 start to the season. The situation was so dire that athletic director Trev Alberts made the move only three weeks before Frost's contract buyout would have been cut in half. The Cornhuskers lost 45-42 to Georgia Southern as a three-touchdown favorite at home on Saturday night. Frost was 16-31 three games into his fifth season. Associate head coach Mickey Joseph was named interim coach for the rest of the season. Alberts said there was no attempt to negotiate a lower buyout and that Frost would receive the $15 million owed to him.
SUNDAY SCORES
INTERLEAGUE
Final Seattle 8 Atlanta 7
AMERICAN LEAGUE
Final Boston 1 Baltimore 0
Final Kansas City 4 Detroit 0
Final N.Y. Yankees 10 Tampa Bay 4
Final Cleveland 4 Minnesota 1
Final Houston 12 L.A. Angels 4
Final Texas 4 Toronto 1
Final Oakland 10 Chicago White Sox 3
NATIONAL LEAGUE
Final St. Louis 4 Pittsburgh 3
Final Philadelphia 7 Washington 5
Final N.Y. Mets 9 Miami 3
Final Milwaukee 7 Cincinnati 6
Final Arizona 12 Colorado 6
Final L.A. Dodgers 11 San Diego 2
Final San Francisco 4 Chicago Cubs 2
NATIONAL FOOTBALL LEAGUE
Final Baltimore 24 N-Y Jets 9
Final Chicago 19 San Francisco 10
Final Cleveland 26 Carolina 24
Final OT Indianapolis 20 Houston 20
Final Miami 20 New England 7
Final New Orleans 27 Atlanta 26
Final Philadelphia 38 Detroit 35
Final OT Pittsburgh 23 Cincinnati 20
Final Washington 28 Jacksonville 22
Final Kansas City 44 Arizona 21
Final L.A. Chargers 24 Las Vegas 19
Final Minnesota 23 Green Bay 7
Final N-Y Giants 21 Tennessee 20
Final Tampa Bay 19 Dallas 3
Mon Denver at Seattle 8:15 p.m.